Corrigendum to "Characterization of the CYP2D6 drug metabolizing phenotypes of the Chilean mestizo population through polymorphism analyses" [Pharm. Res. 101 (November) (2015) 124-129].
نویسندگان
چکیده
Since the publication of this article [1] the authors have noticed that in Fig. 1D, the genotype *2/*2xN was not identified in the adjacent ane to the standard (Std) line. In addition, in the Introduction the statement “We studied the presence of CYP2D6*2 (2850C>T, rs1135840, 296C)” should be read as “We studied the presence of CYP2D6*2 (2850C>T, rs16947, R296C)”. “rs1135840” in Table 2 should have been rs16947”. The statistical analyses of Table 3 were done using the chi squared test and not the one-way ANOVA and Student’s test. The authors apologise for any inconvenience these mistakes may have caused.
منابع مشابه
Characterization of the CYP2D6 drug metabolizing phenotypes of the Chilean mestizo population through polymorphism analyses.
We tested the influence of four polymorphisms and gene duplication in CYP2D6 on in vivo enzyme activity in a Chilean mestizo population in order to identify the most relevant genetic profiles that account for observed phenotypes in this ethnic group. CYP2D6*2 (2850C>T), *3 (2549A>del), *4 (1846G>A), *17 (1023C>T) and gene duplication were determined by PCR-RFLP or PCRL in a group of 321 healthy...
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We wish to comment on the manuscript “Characterization of he CYP2D6 drug metabolizing phenotypes of the Chilean mestizo opulation through polymorphism analyses” [1]. This report has n our opinion serious conceptual shortcomings in basic genetics, opulation genetics and statistics. The authors tested for three allees, CYP2D6*2, CYP2D6*3, CYP2D6*4, they summarize their results in able 3. They com...
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عنوان ژورنال:
- Pharmacological research
دوره 110 شماره
صفحات -
تاریخ انتشار 2016